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1

Synthesis and antitubercular activity of 6-chloro (unsubstituted)-2-methoxy-9-substituted acridine derivatives

Enayat I. Aly, Ashraf H. Abadi

Journal:

Archives of Pharmacal Research

Year:

2004

Language:

english

File:

PDF, 933 KB

english, 2004

2

Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors

Ashraf H. Abadi, Tamer M. Ibrahim, Khaled M. Abouzid, Jochen Lehmann, Heather N. Tinsley, Bernard D. Gary, Gary A. Piazza

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.13 MB

english, 2009

3

Discovery and Optimization of 1,3,5-Trisubstituted Pyrazolines as Potent and Highly Selective Allosteric Inhibitors of Protein Kinase C-ζ

Abdel-Halim, Mohammad, Diesel, Britta, Kiemer, Alexandra K., Abadi, Ashraf H., Hartmann, Rolf W., Engel, Matthias

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 4.62 MB

english, 2014

4

An Interactive SAR Approach to Discover Novel Hybrid Thieno Probes as Ligands for D2-Like Receptors with Affinities in the Subnanomolar Range

Abdel-Fattah, Mohamed A. O., Lehmann, Jochen, Abadi, Ashraf H.

Journal:

Chemistry & Biodiversity

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

5

Synthesis of novel 1,2-diarylpyrazolidin-3-oneâbased compounds and their evaluation as broad spectrum antibacterial agents

Mokbel, Salma A., Fathalla, Reem K., El-Sharkawy, Lina Y., Abadi, Ashraf H., Engel, Matthias, Abdel-Halim, Mohammad

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 821 KB

english, 2020

6

5-Substituted 2-Bromoindolo[3,2-b]quinoxalines. A Class of Potential Antitumor Agents with cdc25 Phosphatase Inhibitory Properties

Ashraf H. Abadi

Journal:

Archiv der Pharmazie

Year:

1998

Language:

english

File:

PDF, 356 KB

english, 1998

7

Synthesis and Antitumor Activity of Ethyl 2-Substituted-aminothiazole-4-carboxylate Analogs

Hussein I. El-Subbagh, Ashraf H. Abadi, Jochen Lehmann

Journal:

Archiv der Pharmazie

Year:

1999

Language:

english

File:

PDF, 345 KB

english, 1999

8

Synthesis and Cyclooxygenase Inhibitory Properties of Novel (+) 2-(6-Methoxy-2-naphthyl)propanoic Acid (Naproxene) Derivatives

Ashraf H. Abadi, Stefan Laufer, Jochen Lehmann

Journal:

Archiv der Pharmazie

Year:

2001

Language:

english

File:

PDF, 66 KB

english, 2001

9

Dopamine/Serotonin Receptor Ligands, Part III [1]: Synthesis and Biological Activities of 7, 7′—Alkylene-bis-6, 7, 8, 9, 14, 15-hexahydro-5H-benz[d]indolo[2, 3-g]azecines — Application of the Bivalent Ligand Approach to a Novel Type of Dopamine Receptor Antagonist

Ashraf H. Abadi, Stefan Lankow, Barbara Hoefgen, Michael Decker, Matthias U. Kassack, Jochen Lehmann

Journal:

Archiv der Pharmazie

Year:

2002

Language:

english

File:

PDF, 115 KB

english, 2002

10

Phenylpiperazinylmethylheterocycle Derivatives: Synthesis and Dopamine Receptor Binding Profiles

Ashraf H. Abadi

Journal:

Archiv der Pharmazie

Year:

2004

Language:

english

File:

PDF, 114 KB

english, 2004

11

Design, Synthesis and Structure–Activity Relationship of Functionalized Tetrahydro-β-carboline Derivatives as Novel PDE5 Inhibitors

Nermin S. Ahmed, Bernard D. Gary, Hethar N. Tinsley, Gary A. Piazza, Stefan Laufer, Ashraf H. Abadi

Journal:

Archiv der Pharmazie

Year:

2011

Language:

english

File:

PDF, 360 KB

english, 2011

12

ChemInform Abstract: 5-Substituted 2-Bromoindolo[3,2-b]quinoxalines. A Class of Potential Antitumor Agents with cdc25 Phosphatase Inhibitory Properties.

Ashraf H. Abadi

Journal:

Year:

1999

File:

PDF, 33 KB

1999

13

ChemInform Abstract: Synthesis, Antitumor and Antitubercular Evaluation of Certain New Xanthenone and Acridinone Analogues.

Ashraf H. Abadi, Hussein I. El-Subbagh, Hamad A. Al-Khamees

Journal:

Year:

1999

File:

PDF, 31 KB

1999

14

ChemInform Abstract: 2,4-Disubstituted Thiazoles. Part 3. Synthesis and Antitumor Activity of Ethyl 2-Substituted-aminothiazole-4-carboxylate Analogues.

Hussein I. El-Subbagh, Ashraf H. Abadi, Jochen Lehmann

Journal:

Year:

1999

File:

PDF, 28 KB

1999

15

ChemInform Abstract: Synthesis of 4-Alkyl(Aryl)-6-aryl-3-cyano-2(1H)-pyridinones and Their 2-Imino Isosteres as Nonsteroidal Cardiotonic Agents.

Ashraf Abadi, Omar Al-Deeb, Ahmed Al-Afify, Hassan El-Kashef

Journal:

Year:

1999

File:

PDF, 29 KB

1999

16

ChemInform Abstract: Synthesis and Cyclooxygenase Inhibitory Properties of Novel (+) 2-(6-Methoxy-2-naphthyl)propanoic Acid (Naproxene) Derivatives.

Ashraf H. Abadi, Stefan Laufer, Jochen Lehmann

Journal:

Year:

2001

File:

PDF, 34 KB

2001

17

Dopamine/Serotonin Receptor Ligands. Part 3. Synthesis and Biological Activities of 7,7′-Alkylene-bis-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo [2,3-g]azecines — Application of the Bivalent Ligand Approach to a Novel Type of Dopamine Receptor Antagonist.

Ashraf H. Abadi, Stefan Lankow, Barbara Hoefgen, Michael Decker, Matthias U. Kassack, Jochen Lehmann

Journal:

Year:

2003

File:

PDF, 107 KB

2003

18

Synthesis of Novel 1,3,4-Trisubstituted Pyrazole Derivatives and Their Evaluation as Antitumor and Antiangiogenic Agents.

Ashraf Hassan Abadi, Amal Abdel Haleem Eissa, Ghaneya Sayed Hassan

Journal:

Year:

2003

File:

PDF, 114 KB

2003

19

Synthesis and Evaluation of Novel 7-Trifluoromethyl-4-(4-substituted anilino)quinolines as Antiparasitic and Antineoplastic Agents.

Ashraf H. Abadi, Reto Brun

Journal:

Year:

2003

File:

PDF, 132 KB

2003

20

ChemInform Abstract: Synthesis of Novel Tadalafil Analogues and Their Evaluation as Phosphodiesterase Inhibitors and Anticancer Agents.

Ashraf H. Abadi, Dalal A. Abouel-Ella, Nermin S. Ahmed, Bernard D. Gary, Jose T. Thaiparambil, Heather N. Tinsley, Adam B. Keeton, Gary A. Piazza

Journal:

Year:

2009

File:

PDF, 33 KB

2009

21

ChemInform Abstract: Discovery of Colon Tumor Cell Growth Inhibitory Agents Through a Combinatorial Approach.

Ashraf H. Abadi, Dalal A. Aboued-Ella, Jochen Lehmann, Heather N. Tinsley, Bernard D. Gary, Gary A. Piazza, Mohammed A. O. Abdel-Fattah

Journal:

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

22

ChemInform Abstract: Synthesis, Molecular Modeling and Biological Evaluation of Novel Tadalafil Analogues as Phosphodiesterase 5 and Colon Tumor Cell Growth Inhibitors, New Stereochemical Perspective.

Ashraf H. Abadi, Bernard D. Gary, Heather N. Tinsley, Gary A. Piazza, Mohammad Abdel-Halim

Journal:

Year:

2010

File:

PDF, 27 KB

2010

23

ChemInform Abstract: Design, Synthesis and Structure—Activity Relationship of Functionalized Tetrahydro-β-carboline Derivatives as Novel PDE5 Inhibitors.

Nermin S. Ahmed, Bernard D. Gary, Hethar N. Tinsley, Gary A. Piazza, Stefan Laufer, Ashraf H. Abadi

Journal:

Year:

2011

File:

PDF, 37 KB

2011

24

High-performance liquid chromatographic determination of diltiazem and two of its metabolites in plasma using a short alkyl chain silanol deactivated column

David R. Rutledge, Ashraf H. Abadi, Larry M. Lopez, Charles A. Beaudreau

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 542 KB

english, 1993

25

Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents

Ashraf H. Abadi, Gehan H. Hegazy, Asmaa A. El-Zaher

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 249 KB

english, 2005

26

Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D4-selective ligand

Fadi M. Awadallah, Franziska Müller, Jochen Lehmann, Ashraf H. Abadi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 185 KB

english, 2007

27

Liquid chromatographic determination of celiprolol, diltiazem, desmethyldiltiazem and deacetyldiltiazem in plasma using a short alkyl chain silanol deactivated column

David R. Rutledge, Ashraf H. Abadi, Larry M. Lopez

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1994

Language:

english

File:

PDF, 578 KB

english, 1994

28

Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands

Noha A. Osman, Amr H. Mahmoud, Marco Allarà, Raimund Niess, Khaled A. Abouzid, Vincenzo Di Marzo, Ashraf H. Abadi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.96 MB

english, 2010

29

Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents

Ashraf H. Abadi, Sahar M. Abou-Seri, Doaa E. Abdel-Rahman, Christian Klein, Olivier Lozach, Laurent Meijer

Journal:

European Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 506 KB

english, 2006

30

Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach

Ashraf H. Abadi, Dalal A. Abouel-Ella, Jochen Lehmann, Heather N. Tinsley, Bernard D. Gary, Gary A. Piazza, Mohammed A.O. Abdel-Fattah

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

31

Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective

Ashraf H. Abadi, Bernard D. Gary, Heather N. Tinsley, Gary A. Piazza, Mohammad Abdel-Halim

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

32

Antibiotic Resistance of Helicobacter pylori in Mazandaran, North of Iran

Amin Talebi Bezmin Abadi, Ashraf M. Mobarez, Tarang Taghvaei, Lutz Wolfram

Journal:

Year:

2010

Language:

english

File:

PDF, 369 KB

english, 2010

33

Frequency of antibiotic resistance inHelicobacter pyloristrains isolated from the northern population of Iran

Amin Talebi Bezmin Abadi, Tarang Taghvaei, Ashraf Mohabbati Mobarez, Beth M. Carpenter, D. Scott Merrell

Journal:

Journal of Microbiology

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

34

Synthesis of 4-alkyl (aryl)-6-aryl-3-cyano-2(1H)-pyridinones and their 2-imino isosteres as nonsteroidal cardiotonic agents

Ashraf Abadi, Omar Al-Deeb, Ahmed Al-Afify, Hassan El-Kashef

Journal:

Year:

1999

Language:

english

File:

PDF, 156 KB

english, 1999

35

Synthesis and biological evaluation of imidazolylmethylacridones as cytochrome P-450 enzymes inhibitors

Abadi, Ashraf H., Abou-Seri, Sahar M., Hu, Qingzhong, Negri, Matthias, Hartmann, Rolf W.

Journal:

Year:

2012

Language:

english

File:

PDF, 734 KB

english, 2012

36

An overview of liquid phase microextraction approaches combined with UV–Vis spectrophotometry

Malihe Dehghani Mohammad Abadi, Narges Ashraf, Mahmoud Chamsaz, Farzaneh Shemirani

Journal:

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

37

Design of Novel β-Carboline Derivatives with Pendant 5-Bromothienyl and Their Evaluation as Phosphodiesterase-5 Inhibitors

El-Gamil, Dalia S., Ahmed, Nermin S., Gary, Bernard D., Piazza, Gary A., Engel, Matthias, Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Archiv der Pharmazie

Year:

2013

Language:

english

File:

PDF, 279 KB

english, 2013

38

Primary resistance ofHelicobacter pylorito levofloxacin and moxifloxacine in Iran

Amin Talebi Bezmin Abadi, Ali Ghasemzadeh, Tarang Taghvaei, Ashraf Mohabbati Mobarez

Journal:

Internal and Emergency Medicine

Year:

2012

Language:

english

File:

PDF, 218 KB

english, 2012

39

Prevalence ofhorBgene among theHelicobacter pyloristrains isolated from dyspeptic patients: first report from Iran

Tarang Taghvaei, Amin Talebi Bezmin Abadi, Ali Ghasemzadeh, Behnam Kalali Naderi, Ashraf Mohabbati Mobarez

Journal:

Internal and Emergency Medicine

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

40

Low frequency ofcagA-positiveHelicobacter pyloristrains isolated from Iranian patients with MALT lymphoma

Amin Talebi Bezmin Abadi, Ali Ghasemzadeh, Ashraf Mohabati Mobarez

Journal:

Internal and Emergency Medicine

Year:

2013

Language:

english

File:

PDF, 210 KB

english, 2013

41

Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives

Ahmed, Nermin S., Ali, Amal H., El-Nashar, Shreen M., Gary, Bernard D., Fajardo, Alexandra M., Tinsley, Heather N., Piazza, Gary A., Negri, Matthias, Abadi, Ashraf H.

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.41 MB

english, 2012

42

Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents

Arafa, Reem K., Hegazy, Gehan H., Piazza, Gary A., Abadi, Ashraf H.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

43

6-Aryl and Heterocycle Quinazoline Derivatives as Potent EGFR Inhibitors with Improved Activity toward Gefitinib-Sensitive and -Resistant Tumor Cell Lines

Hamed, Mostafa M., Abou El Ella, Dalal A., Keeton, Adam B., Piazza, Gary A., Abadi, Ashraf H., Hartmann, Rolf W., Engel, Matthias

Journal:

Year:

2013

Language:

english

File:

PDF, 719 KB

english, 2013

44

Discovery of highly potent and selective D4 ligands by interactive SAR study

Abdelfattah, Mohamed A.O., Lehmann, Jochen, Abadi, Ashraf H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 683 KB

english, 2013

45

Synthesis and Molecular Modeling of Novel Tetrahydro-β-carboline Derivatives with Phosphodiesterase 5 Inhibitory and Anticancer Properties

Mohamed, Heba A., Girgis, Nancy M. R., Wilcken, Rainer, Bauer, Matthias R., Tinsley, Heather N., Gary, Bernard D., Piazza, Gary A., Boeckler, Frank M., Abadi, Ashraf H.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.61 MB

english, 2011

46

One-Pot Synthesis of 4,6-Diaryl-2-oxo(imino)-1,2-dihydropyridine-3-carbonitrile; a New Scaffold for p38α MAP Kinase Inhibition

Serry, Aya M., Luik, Sabine, Laufer, Stefan, Abadi, Ashraf H.

Journal:

Journal of Combinatorial Chemistry

Year:

2010

Language:

english

File:

PDF, 3.17 MB

english, 2010

47

Quinazoline and tetrahydropyridothieno[2,3-d]pyrimidine derivatives as irreversible EGFR tyrosine kinase inhibitors: influence of the position 4 substituent

Hamed, Mostafa M., Abou El Ella, Dalal A., Keeton, Adam B., Piazza, Gary A., Engel, Matthias, Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Year:

2013

Language:

english

File:

PDF, 297 KB

english, 2013

48

Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53

Abdel-Halim, Mohammad, Keeton, Adam B., Gurpinar, Evrim, Gary, Bernard D., Vogel, Simon M., Engel, Matthias, Piazza, Gary A., Boeckler, Frank M., Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 994 KB

english, 2013

49

Clinical relevance of thecagA,tnpAandtnpBgenes inHelicobacter pylori

Abadi, Amin Talebi, Mobarez, Ashraf, Bonten, Marc JM, Wagenaar, Jaap A, Kusters, Johannes G

Journal:

BMC Gastroenterology

Year:

2014

Language:

english

File:

PDF, 172 KB

english, 2014

50

Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes

Taher, Azza T., Kadry, Hanan H., Allarà, Marco, Di Marzo, Vincenzo, Abadi, Ashraf H., Abouzid, Khaled A.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 938 KB

english, 2013